Package: joineR
Type: Package
Title: Joint Modelling of Repeated Measurements and Time-to-Event Data
Version: 1.2.8
Authors@R: c(
    person("Pete", "Philipson", email = "peter.philipson1@newcastle.ac.uk", 
        role = "aut",
        comment = c(ORCID = "0000-0001-7846-0208")),
    person("Ines", "Sousa", email = "isousa@mct.uminho.pt",
        role = "aut",
        comment = c(ORCID = "0000-0002-2712-1713")),
    person("Peter J.", "Diggle", email = "p.diggle@lancaster.ac.uk",
        role = "aut",
        comment = c(ORCID = "0000-0003-3521-5020")),
    person("Paula", "Williamson", email = "p.r.williamson@liverpool.ac.uk",
        role = "aut",
        comment = c(ORCID = "0000-0001-9802-6636")),        
    person("Ruwanthi", "Kolamunnage-Dona", email = "kdrr@liverpool.ac.uk", 
        role = "aut",
        comment = c(ORCID = "0000-0003-3886-6208")),
    person("Robin", "Henderson", email = "robin.henderson@ncl.ac.uk",
        role = "aut"),
    person("Graeme L.", "Hickey", email = "graemeleehickey@gmail.com", 
        role = c("aut", "cre"),
        comment = c(ORCID = "0000-0002-4989-0054")),
    person("Maria", "Sudell", email = "m.e.sudell@liverpool.ac.uk",
        role = "ctb"),
    person("Medical Research Council", role = "fnd",
        comment = "Grant numbers: G0400615 and MR/M013227/1")
    )
Encoding: UTF-8
Description: Analysis of repeated measurements and time-to-event data via random
    effects joint models. Fits the joint models proposed by Henderson and colleagues
    <doi:10.1093/biostatistics/1.4.465> (single event time) and by Williamson and
    colleagues (2008) <doi:10.1002/sim.3451> (competing risks events time) to a
    single continuous repeated measure. The time-to-event data is modelled using a 
    (cause-specific) Cox proportional hazards regression model with time-varying 
    covariates. The longitudinal outcome is modelled using a linear mixed effects
    model. The association is captured by a latent Gaussian process. The model is 
    estimated using am Expectation Maximization algorithm. Some plotting functions 
    and the variogram are also included. This project is funded by the Medical 
    Research Council (Grant numbers G0400615 and MR/M013227/1).
License: GPL-3 | file LICENSE
URL: https://github.com/graemeleehickey/joineR/
BugReports: https://github.com/graemeleehickey/joineR/issues
LazyData: true
ByteCompile: true
Depends: R (>= 3.6), survival
Imports: graphics, lattice, MASS, nlme, statmod, stats, utils
Suggests: knitr, rmarkdown, testthat, covr
VignetteBuilder: knitr
RoxygenNote: 7.1.2
NeedsCompilation: no
Packaged: 2023-01-20 18:09:15 UTC; hickey
Author: Pete Philipson [aut] (<https://orcid.org/0000-0001-7846-0208>),
  Ines Sousa [aut] (<https://orcid.org/0000-0002-2712-1713>),
  Peter J. Diggle [aut] (<https://orcid.org/0000-0003-3521-5020>),
  Paula Williamson [aut] (<https://orcid.org/0000-0001-9802-6636>),
  Ruwanthi Kolamunnage-Dona [aut]
    (<https://orcid.org/0000-0003-3886-6208>),
  Robin Henderson [aut],
  Graeme L. Hickey [aut, cre] (<https://orcid.org/0000-0002-4989-0054>),
  Maria Sudell [ctb],
  Medical Research Council [fnd] (Grant numbers: G0400615 and
    MR/M013227/1)
Maintainer: Graeme L. Hickey <graemeleehickey@gmail.com>
Repository: CRAN
Date/Publication: 2023-01-22 21:20:06 UTC
Built: R 4.6.0; ; 2026-06-02 03:07:55 UTC; windows
